Azithromycin-induced severe Thrombocytopenia: A rare entity

Drug-induced thrombocytopenia (DITP) is a well-established but underdiagnosed condition. The condition is mostly asymptomatic, but can also cause severe bleeding [1]. Thrombocytopenia is a wellknown side effect of treatment with several types of medications. Therapeutic agents, speci ically those used for chemotherapy and immunosuppressants, tend to repress hematopoiesis and generate pancytopenia [2]. Azithromycin is a macrolide antibiotic used for bacterial infections (i.e., respiratory, urogenital, dermal), and has immunomodulatory properties to ight chronic in lammatory disorders [3]. This drug is easy to take and has minimal adverse effects including diarrhea, abdominal pain, and mild headache [4]. Although DITP cases are well-known, severe thrombocytopenia caused by azithromycin is very rare. In fact, to our knowledge, there are no previous cases reported on this. Abbreviations